KMID : 0614620120590060414
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Korean Journal of Gastroenterology 2012 Volume.59 No. 6 p.414 ~ p.422
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Comparison among Conventional 4 L Polyethylene Glycol, Split Method of 4 L Polyethylene Glycol and Combination of 2 L Polyethylene Glycol and Sodium Phosphate Solution for Colonoscopy Preparation
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Jo So-Young
Kim Na-Young Lee Jung-Won Lim Ji-Hwan Choi Chi-Un Chon Il-Young Kil Ho Min Bo-Young Byoun Young-Sang Lee Ban-Seok Jang Sang-Eon Park Hyun-Kyung Jo Hyun-Jin Shin Cheol-Min Lee Sang-Hyub Park Young-Soo Hwang Jin-Hyeok Kim Jin-Wook Jeong Sook-Hyang Lee Dong-Ho
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Abstract
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Background/Aims: The aim of this study was to compare polyethylene glycol (PEG) 4 L, split method of PEG 4 L and PEG 2 L plus sodium phosphate (NaP) in the aspect of bowel preparation quality, safety, patients¡¯ compliance and preference.
Methods: Total 249 subjects were prospectively enrolled and received bowel preparation for colonoscopy from August to October in 2010; PEG 4 L (93 subjects), split method of 4 L PEG (74 subjects) and PEG 2 L plus NaP 90 mL group (82 subjects). To investigate the completion, preference for bowel preparation and safety, a questionnaire survey was conducted before colonoscopy.
Results: There were no significant intergroup differences in the aspect of completion of preparation, cecal intubation time and success rate. Satisfaction and preference were higher in PEG 2 L plus NaP 90 mL and split method of 4 L PEG compared with PEG 4 L. In the aspect of the bowel preparation quality PEG 4 L showed significantly higher quality in the morning colonoscopy (p<0.001). However, in the afternoon colonoscopy PEG 2 L plus NaP 90 mL showed better result than PEG 4 L (p=0.009). Hyperphosphatemia was most frequently observed in PEG 2 L plus NaP 90 mL, but no severe adverse events occurred (p<0.001).
Conclusions: PEG 4 L showed better result than split method of 4 L PEG or PEG 2 L plus NaP 90 mL in the aspect of bowel preparation quality and safety. (Korean J Gastroenterol 2012;59:414-422)
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KEYWORD
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Colonoscopy, Bowel preparation solution, Polyethylene glycols, Sodium phosphate
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